Meryl Comer - A Caregiver’s Account of Alzheimer’s.
A woman is like a teabag. You never know how strong she is until she's in hot water.
Meryl is President and CEO of Geoffrey Beene Foundation Alzheimer's Initiative, which promotes early diagnosis, virtual innovation challenges, m-health technologies and national public service campaigns. She is a Co-Founder of WomenAgainstAlzheimer's and Founding Partner of the Global Alliance on Women's Brain Health. Meryl is also Co-Principal Investigator for the PCORI Alzheimer's, Dementia, Patient & Caregiver Powered Research Network (funded by PCORI), a partnership of the Mayo Clinic, UCSF Brain Health Registry and UsAgainstAlzheimer's. She is a veteran broadcast journalist. Her New York Times
bestseller, Slow Dancing with a Stranger: Lost and Found in the Age of Alzheimer's
(HarperCollins) is an unflinching account of her husband’s early onset Alzheimer’s disease and a “much-needed wake-up call for an honest dialogue about this fatal neurodegenerative disease.” All of the proceeds support Alzheimer's research.
Cognitive impairment/dementia is the major and rapidly increasing human, social and economic burden globally. Prevention has been highlighted as the key element in managing the dementia epidemic. It has been estimated that at least 30% of Alzheimer’s Disease (the largest form of dementia) is related to conditions that can be influenced, including blood pressure, diabetes, obesity, physical activity, depression, and education (Kivipelto, Ngandu et al. Nature Reviews Neurology 2018)
Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is a pioneering randomized clinical trial and the first in the world to show that a multidomain lifestyle-based 2-year intervention including diet, exercise, cognitive training and vascular and metabolic risk management can significantly reduce the risk of cognitive decline among at risk elderly persons from general population (Ngandu, Kivipelto et al,
The Lancet, 2015, 385: 2255-63).
No Alzheimer’s Disease drug trial has yet shown such an effect.
The intervention was beneficial even in people with genetic susceptibility for dementia. It can improve health-related quality of life and reduce the risk of other chronic diseases (risk of multimorbidity was 60% lower). All these outcomes are crucial for healthy and active aging.”
FINGER has caused a paradigm shift, i.e. cognitive decline is no longer an inevitable consequence of aging, but can be prevented with multidomain interventions. The study has resulted in a large global interest in follow-up and expansion of the initial FINGER study. Professor Kivipelto and her team have now launched and are leading the global effort called World-Wide FINGER (
www.alz.org/wwfingers), a unique interdisciplinary network to share experience, harmonize data, and plan joint international initiatives for the prevention of cognitive impairment/dementia. Researchers from 15 countries around the world are already carrying out or are about to start a number of clinical trials based on the FINGER protocol.